Estrogenicity of Styrene Oligomers: Response to Ohno etal.
نویسندگان
چکیده
منابع مشابه
Estrogenicity of styrene oligomers and assessment of estrogen receptor binding assays.
Polystyrene is frequently used in resins, and the styrene dimers and trimers eluted from polystyrene have been reported to have estrogenic activity (1). We have performed a number of in vitro and in vivo tests [i.e., estrogen receptor (ER) and androgen receptor binding assays, thyroid hormone receptor binding assays, human breast cancer cell line MCF-7 proliferation assays (E-SCREEN), uterotrop...
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The gas-phase conformations of poly(styrene) oligomers cationized by Li+, Na+, Cu+, and Ag+ (M+ PSn) were examined using ion mobility experiments and molecular mechanics/ dynamics calculations. M+PSn ions were formed by MALDI and their ion-He collision cross-sections were measured by ion mobility methods. The experimental collision cross-sections of each M+PS n-mer were similar for all four met...
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In a recent article (Dormann et al., 2012, Journal of Biogeography, 39, 2119–2131), we compared different approaches to species distribution modelling and depicted modelling approaches along an axis from purely ‘correlative’ to ‘forward processbased’ models. In their correspondence, Kriticos et al. (2013, Journal of Biogeography, doi:10.1111/j.1365-2699.2012.02791.x) challenge this view, claimi...
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متن کاملEstrogenic activity of styrene oligomers after metabolic activation by rat liver microsomes.
In this study we examined estrogenic activity of styrene oligomers after metabolic activation by rat liver microsomes. Trans-1,2-diphenylcyclobutane (TCB), cis-1,2-diphenylcyclobutane (CCB), 1,3-diphenylpropane, 2,4-diphenyl-1-butene, 2,4,6-triphenyl-1-hexene, and 1-alpha-phenyl-4ss-(1 -phenylethyl)tetralin were negative in the yeast estrogen screening assay and estrogen reporter assay using es...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2002
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.110-a385